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Genome-Wide CRISPR Screen Reveals Cancer Cell Resistance to NK Cells Induced by NK-Derived IFN-γ

The anti-leukemia activity of NK cells helps prevent relapse during hematopoietic stem cell transplantation (HSCT) in leukemia patients. However, the factors that determine the sensitivity or resistance of leukemia cells in the context of NK-mediated cytotoxicity are not well-established. Here, we p...

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Detalles Bibliográficos
Autores principales:	Zhuang, Xiaoxuan, Veltri, Daniel P., Long, Eric O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917608/ https://www.ncbi.nlm.nih.gov/pubmed/31921143 http://dx.doi.org/10.3389/fimmu.2019.02879

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