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The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis
Laminin-γ1 is required for early embryonic development; however, the need for laminin-γ1 synthesis in adulthood is unknown. A global and inducible mouse model of laminin-γ1 deficiency was generated to address this question. Genetic ablation of the Lamc1 gene in adult mice was rapidly lethal. Despite...
Autores principales: | Fields, British, DeLaForest, Ann, Zogg, Mark, May, Jennifer, Hagen, Catherine, Komnick, Kristin, Wieser, Jon, Lundberg, Alexander, Weiler, Hartmut, Battle, Michele A., Carlson, Karen-Sue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917708/ https://www.ncbi.nlm.nih.gov/pubmed/31848396 http://dx.doi.org/10.1038/s41598-019-55844-x |
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