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Generation of protective pneumococcal-specific nasal resident memory CD4(+) T cells via parenteral immunization

The generation of tissue-resident memory T cells (T(RM)) is an essential aspect of immunity at mucosal surfaces, and it has been suggested that preferential generation of T(RM) is one of the principal advantages of mucosally administered vaccines. We have previously shown that antigen-specific, IL-1...

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Detalles Bibliográficos
Autores principales: O’Hara, Joanne M., Redhu, Naresh S, Cheung, Elaine, Robertson, Nahid G., Patik, Izabel, Sayed, Shorouk El, Thompson, Claudette M., Herd, Muriel, Lucas, Katherine B., Conaway, Evan, Morton, Cynthia C., Farber, Donna L., Malley, Richard, Horwitz, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917870/
https://www.ncbi.nlm.nih.gov/pubmed/31659300
http://dx.doi.org/10.1038/s41385-019-0218-5