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TGFβ1 Single Nucleotide Polymorphism C-509T Alters Mucosal Cell Function in Pediatric Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a chronic Th2 antigen driven disorder associated with tissue remodeling. Inflammation and remodeling lead to esophageal rigidity, strictures, and dysphagia. TGFβ1 drives esophageal remodeling including epithelial barrier dysfunction and subepithelial fibrosis. A fun...

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Detalles Bibliográficos
Autores principales:	Duong, L.D., Rawson, R., Bezryadina, A., Manresa, M.C., Newbury, R.O., Dohil, R., Liu, Z., Barrett, K., Kurten, R., Aceves, S.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917872/ https://www.ncbi.nlm.nih.gov/pubmed/31636346 http://dx.doi.org/10.1038/s41385-019-0214-9

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