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Alanyl-tRNA Synthetase Quality Control Prevents Global Dysregulation of the Escherichia coli Proteome

Mechanisms have evolved to prevent errors in replication, transcription, and translation of genetic material, with translational errors occurring most frequently. Errors in protein synthesis can occur at two steps, during tRNA aminoacylation and ribosome decoding. Recent advances in protein mass spe...

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Detalles Bibliográficos
Autores principales: Kelly, Paul, Backes, Nicholas, Mohler, Kyle, Buser, Christopher, Kavoor, Arundhati, Rinehart, Jesse, Phillips, Gregory, Ibba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918089/
https://www.ncbi.nlm.nih.gov/pubmed/31848288
http://dx.doi.org/10.1128/mBio.02921-19

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