Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)

In article number https://doi.org/10.1002/advs.201901822, King Wai Chiu Lai, Zhifeng Huang, Ken Kin Lam Yung, and co‐workers develop a biocompatible silica sculptured in nanozigzags by glancing angle deposition. The nanomatrix induces self‐organization of neural stem cells into miniature substantia...

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Detalles Bibliográficos
Autores principales: Zhang, Shiqing, Sun, Peng, Lin, Kaili, Chan, Florence Hiu Ling, Gao, Qi, Lau, Wai Fung, Roy, Vellaisamy A. L., Zhang, Hongqi, Lai, King Wai Chiu, Huang, Zhifeng, Yung, Ken Kin Lam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918097/
http://dx.doi.org/10.1002/advs.201970144
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author Zhang, Shiqing
Sun, Peng
Lin, Kaili
Chan, Florence Hiu Ling
Gao, Qi
Lau, Wai Fung
Roy, Vellaisamy A. L.
Zhang, Hongqi
Lai, King Wai Chiu
Huang, Zhifeng
Yung, Ken Kin Lam
author_facet Zhang, Shiqing
Sun, Peng
Lin, Kaili
Chan, Florence Hiu Ling
Gao, Qi
Lau, Wai Fung
Roy, Vellaisamy A. L.
Zhang, Hongqi
Lai, King Wai Chiu
Huang, Zhifeng
Yung, Ken Kin Lam
author_sort Zhang, Shiqing
collection PubMed
description In article number https://doi.org/10.1002/advs.201901822, King Wai Chiu Lai, Zhifeng Huang, Ken Kin Lam Yung, and co‐workers develop a biocompatible silica sculptured in nanozigzags by glancing angle deposition. The nanomatrix induces self‐organization of neural stem cells into miniature substantia nigra‐like brain structures, which could deliver early and progressive amelioration in Parkinsonian rats. These results provide significant insight into novel cell therapies for Parkinson's disease. [Image: see text]
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spelling pubmed-69180972019-12-23 Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019) Zhang, Shiqing Sun, Peng Lin, Kaili Chan, Florence Hiu Ling Gao, Qi Lau, Wai Fung Roy, Vellaisamy A. L. Zhang, Hongqi Lai, King Wai Chiu Huang, Zhifeng Yung, Ken Kin Lam Adv Sci (Weinh) Inside Front Cover In article number https://doi.org/10.1002/advs.201901822, King Wai Chiu Lai, Zhifeng Huang, Ken Kin Lam Yung, and co‐workers develop a biocompatible silica sculptured in nanozigzags by glancing angle deposition. The nanomatrix induces self‐organization of neural stem cells into miniature substantia nigra‐like brain structures, which could deliver early and progressive amelioration in Parkinsonian rats. These results provide significant insight into novel cell therapies for Parkinson's disease. [Image: see text] John Wiley and Sons Inc. 2019-12-18 /pmc/articles/PMC6918097/ http://dx.doi.org/10.1002/advs.201970144 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Front Cover
Zhang, Shiqing
Sun, Peng
Lin, Kaili
Chan, Florence Hiu Ling
Gao, Qi
Lau, Wai Fung
Roy, Vellaisamy A. L.
Zhang, Hongqi
Lai, King Wai Chiu
Huang, Zhifeng
Yung, Ken Kin Lam
Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)
title Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)
title_full Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)
title_fullStr Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)
title_full_unstemmed Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)
title_short Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)
title_sort parkinson's disease: extracellular nanomatrix‐induced self‐organization of neural stem cells into miniature substantia nigra‐like structures with therapeutic effects on parkinsonian rats (adv. sci. 24/2019)
topic Inside Front Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918097/
http://dx.doi.org/10.1002/advs.201970144
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