Polymer Nanocontainers: Controlled Cellular Delivery of Amphiphilic Cargo by Redox‐Responsive Nanocontainers (Adv. Sci. 24/2019)

In article number https://doi.org/10.1002/advs.201901935, Volker Gerke, Bart Jan Ravoo, and co‐workers design novel polymer nanocontainers, based on redox‐responsive cyclodextrin amphiphiles mixed with phospholipids and encapsulated in a cystamine‐crosslinked polymer shell, to deliver amphiphilic ca...

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Detalles Bibliográficos
Autores principales: de Vries, Wilke C., Kudruk, Sergej, Grill, David, Niehues, Maximilian, Matos, Anna Livia Linard, Wissing, Maren, Studer, Armido, Gerke, Volker, Ravoo, Bart Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Inside Back Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918102/
http://dx.doi.org/10.1002/advs.201970146
Descripción
Sumario:In article number https://doi.org/10.1002/advs.201901935, Volker Gerke, Bart Jan Ravoo, and co‐workers design novel polymer nanocontainers, based on redox‐responsive cyclodextrin amphiphiles mixed with phospholipids and encapsulated in a cystamine‐crosslinked polymer shell, to deliver amphiphilic cargo, specifically labeled phospholipids, into human cells. Due to the redox‐sensitive cyclodextrin core and polymer shell, cargo is released inside the cell's reductive endosomal compartment. [Image: see text]

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