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m(6)A modification-mediated CBX8 induction regulates stemness and chemosensitivity of colon cancer via upregulation of LGR5

BACKGROUND: Colon cancer (CC) cells can exhibit stemness and expansion capabilities, which contribute to resistance to conventional chemotherapies. Aberrant expression of CBX8 has been identified in many types of cancer, but the cause of this aberrant CBX8 expression and whether CBX8 is associated w...

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Detalles Bibliográficos
Autores principales:	Zhang, Yi, Kang, Min, Zhang, Bin, Meng, Fanchao, Song, Jun, Kaneko, Hiroshi, Shimamoto, Fumio, Tang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918584/ https://www.ncbi.nlm.nih.gov/pubmed/31849331 http://dx.doi.org/10.1186/s12943-019-1116-x

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