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Endothelial-mesenchymal transition harnesses HSP90α-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma

BACKGROUND: Endothelial-to-mesenchymal transition (EndoMT) can provide a source of cancer-associated fibroblasts which contribute to desmoplasia of many malignancies including pancreatic ductal adenocarcinoma (PDAC). We investigated the clinical relevance of EndoMT in PDAC, and explored its underlyi...

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Detalles Bibliográficos
Autores principales:	Fan, Chi-Shuan, Chen, Li-Li, Hsu, Tsu-An, Chen, Chia-Chi, Chua, Kee Voon, Li, Chung-Pin, Huang, Tze-Sing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918594/ https://www.ncbi.nlm.nih.gov/pubmed/31847880 http://dx.doi.org/10.1186/s13045-019-0826-2

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