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Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages
BACKGROUND: The circumsporozoite protein (CSP) of Plasmodium is a key surface antigen that induces antibodies and T-cells, conferring immune protection in animal models and humans. However, much of the work on CSP and immunity has been developed based on studies using rodent or non-human primate CSP...
Autores principales: | Flores-Garcia, Yevel, Herrera, Sonia M., Jhun, Hugo, Pérez-Ramos, Daniel W., King, C. Richter, Locke, Emily, Raghunandan, Ramadevi, Zavala, Fidel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918627/ https://www.ncbi.nlm.nih.gov/pubmed/31849326 http://dx.doi.org/10.1186/s12936-019-3055-9 |
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