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Evaluation of gene-environment interactions for colorectal cancer susceptibility loci using case-only and case-control designs
BACKGROUND: Genome-wide association studies (GWAS) have identified more than 40 colorectal cancer susceptibility loci, but only a small fraction of heritability was explained. To account for missing heritability, we investigated gene-environment interactions (G × Es) between GWAS-identified single-n...
Autores principales: | Song, Nan, Lee, Jeeyoo, Cho, Sooyoung, Kim, Jeongseon, Oh, Jae Hwan, Shin, Aesun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918639/ https://www.ncbi.nlm.nih.gov/pubmed/31849324 http://dx.doi.org/10.1186/s12885-019-6456-9 |
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