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Development of human brain organoids with functional vascular-like system

Human cortical organoids (hCOs), derived from human embryonic stem cells (hESCs), provide an excellent platform to study human brain development and diseases in complex 3D tissue. However, current hCOs lack microvasculature, resulting in limited oxygen and nutrient delivery to the inner-most parts o...

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Detalles Bibliográficos
Autores principales:	Cakir, Bilal, Xiang, Yangfei, Tanaka, Yoshiaki, Kural, Mehmet Hamdi, Parent, Maxime, Kang, Young-Jin, Chapeton, Kayley, Patterson, Benjamin, Yuan, Yifan, He, Chang-Shun, Raredon, Micha Sam Brickman, Dengelegi, Jake, Kim, Kun-Yong, Sun, Pingnan, Zhong, Mei, Lee, Sang-Ho, Patra, Prabir, Hyder, Fahmeed, Niklason, Laura E., Lee, Sang-Hun, Yoon, Young-sup, Park, In-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918722/ https://www.ncbi.nlm.nih.gov/pubmed/31591580 http://dx.doi.org/10.1038/s41592-019-0586-5

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