Transgenic minipig model of Huntington's disease exhibiting gradually progressing neurodegeneration

Recently developed therapeutic approaches for the treatment of Huntington's disease (HD) require preclinical testing in large animal models. The minipig is a suitable experimental animal because of its large gyrencephalic brain, body weight of 70-100 kg, long lifespan, and anatomical, physiolog...

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Detalles Bibliográficos
Autores principales: Ardan, Taras, Baxa, Monika, Levinská, Božena, Sedláčková, Miroslava, Nguyen, The Duong, Klíma, Jiří, Juhás, Štefan, Juhásová, Jana, Šmatlíková, Petra, Vochozková, Petra, Motlík, Jan, Ellederová, Zdenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918760/
https://www.ncbi.nlm.nih.gov/pubmed/31645369
http://dx.doi.org/10.1242/dmm.041319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918760/
https://www.ncbi.nlm.nih.gov/pubmed/31645369
http://dx.doi.org/10.1242/dmm.041319

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