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Cytotoxic T Cell-Derived Granzyme B Is Increased in Severe Plasmodium Falciparum Malaria

In Plasmodium falciparum malaria, CD8(+) T cells play a double-edged role. Liver-stage specific CD8(+) T cells can confer protection, as has been shown in several vaccine studies. Blood-stage specific CD8(+) T cells, on the other hand, contribute to the development of cerebral malaria in murine mode...

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Detalles Bibliográficos
Autores principales:	Kaminski, Lea-Christina, Riehn, Mathias, Abel, Annemieke, Steeg, Christiane, Yar, Denis Dekugmen, Addai-Mensah, Otchere, Aminkiah, Francis, Owusu Dabo, Ellis, Jacobs, Thomas, Mackroth, Maria Sophia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918797/ https://www.ncbi.nlm.nih.gov/pubmed/31921176 http://dx.doi.org/10.3389/fimmu.2019.02917

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