Cargando…

Sharing Historical Trial Data to Accelerate Clinical Development

Detalles Bibliográficos
Autores principales:	Yin, Perry T., Desmond, Jules, Day, Julie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Discovery & Development
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918862/ https://www.ncbi.nlm.nih.gov/pubmed/31538661 http://dx.doi.org/10.1002/cpt.1608

Ejemplares similares

Small But Mighty: The Use of Real‐World Evidence to Inform Precision Medicine
por: Miksad, Rebecca A., et al.
Publicado: (2019)

Path Toward Proactive Therapy for Patent Ductus Arteriosus
por: Yamada, Satsuki, et al.
Publicado: (2019)

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database
por: Gaedigk, Andrea, et al.
Publicado: (2017)

Use of Computational Functional Genomics in Drug Discovery and Repurposing for Analgesic Indications
por: Lötsch, Jörn, et al.
Publicado: (2018)

Biobanks in the Era of Digital Medicine
por: Jacobs, Gunnar, et al.
Publicado: (2017)

The Evolution of PharmVar
por: Gaedigk, Andrea, et al.
Publicado: (2018)

Pharmacogene Variation Consortium Gene Introduction: NUDT15
por: Yang, Jun J., et al.
Publicado: (2018)

Historical Contingency Causes Divergence in Adaptive Expression of the lac Operon
por: Karkare, Kedar, et al.
Publicado: (2021)

Historical Contingency Drives Compensatory Evolution and Rare Reversal of Phage Resistance
por: Debray, Reena, et al.
Publicado: (2022)

Historical Introgression from Wild Relatives Enhanced Climatic Adaptation and Resistance to Pneumonia in Sheep
por: Cao, Yin-Hong, et al.
Publicado: (2020)

Shared Evolutionary Path in Social Microbiomes
por: Frazão, Nelson, et al.
Publicado: (2023)

Historic Sampling of a Vanishing Beast: Population Structure and Diversity in the Black Rhinoceros
por: Sánchez-Barreiro, Fátima, et al.
Publicado: (2023)

Genomes From Historic DNA Unveil Massive Hidden Extinction and Terminal Endangerment in a Tropical Asian Songbird Radiation
por: Wu, Meng Yue, et al.
Publicado: (2022)

Origins of Shared Genetic Variation in African Cichlids
por: Loh, Yong-Hwee E., et al.
Publicado: (2013)

Paralog Re-Emergence: A Novel, Historically Contingent Mechanism in the Evolution of Antimicrobial Resistance
por: Hawkins, Nichola J., et al.
Publicado: (2014)

Malagasy Genetic Ancestry Comes from an Historical Malay Trading Post in Southeast Borneo
por: Brucato, Nicolas, et al.
Publicado: (2016)

Recent Historical Migrations Have Shaped the Gene Pool of Arabs and Berbers in North Africa
por: Arauna, Lara R., et al.
Publicado: (2017)

Approximate Bayesian Computation Untangles Signatures of Contemporary and Historical Hybridization between Two Endangered Species
por: Dittberner, Hannes, et al.
Publicado: (2022)

Bipartite Network Analysis of Gene Sharings in the Microbial World
por: Corel, Eduardo, et al.
Publicado: (2018)

Genetic Barriers to Historical Gene Flow between Cryptic Species of Alpine Bumblebees Revealed by Comparative Population Genomics
por: Christmas, Matthew J, et al.
Publicado: (2021)

Hidden Historical Habitat-Linked Population Divergence and Contemporary Gene Flow of a Deep-Sea Patellogastropod Limpet
por: Xu, Ting, et al.
Publicado: (2021)

Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
por: Leurent, C, et al.
Publicado: (2015)

The Evolution and Functional Impact of Human Deletion Variants Shared with Archaic Hominin Genomes
por: Lin, Yen-Lung, et al.
Publicado: (2015)

Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations
por: Jha, Aashish R., et al.
Publicado: (2016)

Accelerated Evolution of Enhancer Hotspots in the Mammal Ancestor
por: Holloway, Alisha K., et al.
Publicado: (2016)

Genomic Analyses of Three Malaria Vectors Reveals Extensive Shared Polymorphism but Contrasting Population Histories
por: O’Loughlin, Samantha M., et al.
Publicado: (2014)

Mitochondrial Genomics Reveals Shared Phylogeographic Patterns and Demographic History among Three Periodical Cicada Species Groups
por: Du, Zhenyong, et al.
Publicado: (2019)

Accelerated Evolution of Developmentally Biased Genes in the Tetraphenic Ant Cardiocondyla obscurior
por: Schrader, Lukas, et al.
Publicado: (2017)

Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses
por: Tollis, Marc, et al.
Publicado: (2021)

The Centromere Histone Is Conserved and Associated with Tandem Repeats Sharing a Conserved 19-bp Box in the Holocentromere of Meloidogyne Nematodes
por: Despot-Slade, Evelin, et al.
Publicado: (2021)

Genome-Wide Identification of Regulatory Sequences Undergoing Accelerated Evolution in the Human Genome
por: Dong, Xinran, et al.
Publicado: (2016)

Developmental Loci Harbor Clusters of Accelerated Regions That Evolved Independently in Ape Lineages
por: Kostka, Dennis, et al.
Publicado: (2018)

Differential Gene Expression in the Human Brain Is Associated with Conserved, but Not Accelerated, Noncoding Sequences
por: Meyer, Kyle A., et al.
Publicado: (2017)

Gene Duplication Accelerates the Pace of Protein Gain and Loss from Plant Organelles
por: Costello, Rona, et al.
Publicado: (2020)

Expansion and Accelerated Evolution of 9-Exon Odorant Receptors in Polistes Paper Wasps
por: Legan, Andrew W, et al.
Publicado: (2021)

A Novel Group of Dynamin-Related Proteins Shared by Eukaryotes and Giant Viruses Is Able to Remodel Mitochondria From Within the Matrix
por: Sheikh, Shaghayegh, et al.
Publicado: (2023)

Human MicroRNAs Originated from Two Periods at Accelerated Rates in Mammalian Evolution
por: Iwama, Hisakazu, et al.
Publicado: (2013)

Accelerated Diversification of Nonhuman Primate Malarias in Southeast Asia: Adaptive Radiation or Geographic Speciation?
por: Muehlenbein, Michael P., et al.
Publicado: (2015)

The Emergence of SARS-CoV-2 Variants of Concern Is Driven by Acceleration of the Substitution Rate
por: Tay, John H, et al.
Publicado: (2022)

Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea
por: Trigila, Anabella P, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k6sd7e1v9kekja54rk5bkroeu1