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Diet Associated with Inflammation and Alzheimer’s Disease
Neurocognitive disorders, such as Alzheimer’s disease (AD), affect millions of people worldwide and are characterized by cognitive decline. Human and animal studies have shown that chronic immune response and inflammation are important factors in the pathogenesis of AD. Chronic inflammation can acce...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918878/ https://www.ncbi.nlm.nih.gov/pubmed/31867568 http://dx.doi.org/10.3233/ADR-190152 |
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author | Vasefi, Maryam Hudson, Mackenzie Ghaboolian-Zare, Ehsan |
author_facet | Vasefi, Maryam Hudson, Mackenzie Ghaboolian-Zare, Ehsan |
author_sort | Vasefi, Maryam |
collection | PubMed |
description | Neurocognitive disorders, such as Alzheimer’s disease (AD), affect millions of people worldwide and are characterized by cognitive decline. Human and animal studies have shown that chronic immune response and inflammation are important factors in the pathogenesis of AD. Chronic inflammation can accelerate the aggregation of amyloid-β peptides and later hyperphosphorylation of tau proteins. The exact etiology of AD is not clear, but genetics and environmental factors, such as age, family history, and lifestyle are linked to neurodegenerative diseases. Lifestyle habits, such as poor diet, are associated with inflammation and could accelerate or slow down the progression of neurodegenerative diseases. Here we provide a review of the potential conditions and factors that stimulate the inflammatory processes in AD. An understanding of inflammatory mechanisms influencing the development of AD may help to protect against dementia and AD. |
format | Online Article Text |
id | pubmed-6918878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-69188782019-12-20 Diet Associated with Inflammation and Alzheimer’s Disease Vasefi, Maryam Hudson, Mackenzie Ghaboolian-Zare, Ehsan J Alzheimers Dis Rep Review Neurocognitive disorders, such as Alzheimer’s disease (AD), affect millions of people worldwide and are characterized by cognitive decline. Human and animal studies have shown that chronic immune response and inflammation are important factors in the pathogenesis of AD. Chronic inflammation can accelerate the aggregation of amyloid-β peptides and later hyperphosphorylation of tau proteins. The exact etiology of AD is not clear, but genetics and environmental factors, such as age, family history, and lifestyle are linked to neurodegenerative diseases. Lifestyle habits, such as poor diet, are associated with inflammation and could accelerate or slow down the progression of neurodegenerative diseases. Here we provide a review of the potential conditions and factors that stimulate the inflammatory processes in AD. An understanding of inflammatory mechanisms influencing the development of AD may help to protect against dementia and AD. IOS Press 2019-11-16 /pmc/articles/PMC6918878/ /pubmed/31867568 http://dx.doi.org/10.3233/ADR-190152 Text en © 2019 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Vasefi, Maryam Hudson, Mackenzie Ghaboolian-Zare, Ehsan Diet Associated with Inflammation and Alzheimer’s Disease |
title | Diet Associated with Inflammation and Alzheimer’s Disease |
title_full | Diet Associated with Inflammation and Alzheimer’s Disease |
title_fullStr | Diet Associated with Inflammation and Alzheimer’s Disease |
title_full_unstemmed | Diet Associated with Inflammation and Alzheimer’s Disease |
title_short | Diet Associated with Inflammation and Alzheimer’s Disease |
title_sort | diet associated with inflammation and alzheimer’s disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918878/ https://www.ncbi.nlm.nih.gov/pubmed/31867568 http://dx.doi.org/10.3233/ADR-190152 |
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