Calcilytic NPS 2143 Reduces Amyloid Secretion and Increases sAβPPα Release from PSEN1 Mutant iPSC-Derived Neurons

Despite numerous efforts and studies over the last three decades, Alzheimer’s disease (AD) remains a disorder not fully understood and incurable so far. Development of induced pluripotent stem cell (iPSC) technology to obtain terminally differentiated neurons from adult somatic cells revolutionized...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo Giudice, Maria, Mihalik, Balázs, Turi, Zsófia, Dinnyés, András, Kobolák, Julianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918902/
https://www.ncbi.nlm.nih.gov/pubmed/31640098
http://dx.doi.org/10.3233/JAD-190602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918902/
https://www.ncbi.nlm.nih.gov/pubmed/31640098
http://dx.doi.org/10.3233/JAD-190602

Ejemplares similares