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Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data
BACKGROUND: In the UK, an estimated one third of people with dementia have not received a diagnosis. Good evidence suggests that dementia risk is increased among widowed individuals; however, it is not clear if they are being diagnosed in routine primary care. OBJECTIVE: This study aimed to investig...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918907/ https://www.ncbi.nlm.nih.gov/pubmed/31594227 http://dx.doi.org/10.3233/JAD-190571 |
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author | Forbes, Harriet J. Wong, Angel Y.S. Morton, Caroline Bhaskaran, Krishnan Smeeth, Liam Richards, Marcus Schmidt, Sigrun A.J. Langan, Sinéad M. Warren-Gash, Charlotte |
author_facet | Forbes, Harriet J. Wong, Angel Y.S. Morton, Caroline Bhaskaran, Krishnan Smeeth, Liam Richards, Marcus Schmidt, Sigrun A.J. Langan, Sinéad M. Warren-Gash, Charlotte |
author_sort | Forbes, Harriet J. |
collection | PubMed |
description | BACKGROUND: In the UK, an estimated one third of people with dementia have not received a diagnosis. Good evidence suggests that dementia risk is increased among widowed individuals; however, it is not clear if they are being diagnosed in routine primary care. OBJECTIVE: This study aimed to investigate if bereavement influenced the probability of having received a dementia diagnosis. METHODS: A population-based cohort study using UK electronic health records, between 1997 and 2017, among 247,586 opposite-sex partners. Those experiencing partner bereavement were matched (age, sex, and date of bereavement) to a non-bereaved person living in a partnership. Multivariate cox regression was performed. RESULTS: Partner bereavement was associated with an increased risk of receiving a diagnosis of dementia in the first three months (hazard ratio (HR) 1.43, 95% CI 1.20–1.71) and first six months (HR 1.24, 95% CI 1.09–1.41), while there was a small reduced risk of getting a dementia diagnosis over all follow-up (HR 0.94, 95% CI 0.89–0.98). CONCLUSIONS: Partner bereavement appears to lead to a short-term increased risk of the surviving partner receiving a diagnosis of dementia, suggesting that bereavement unmasks existing undiagnosed dementia. Over the longer term, however, bereaved individuals are less likely to have a diagnosis of dementia in their health records than non-bereaved individuals. |
format | Online Article Text |
id | pubmed-6918907 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-69189072019-12-20 Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data Forbes, Harriet J. Wong, Angel Y.S. Morton, Caroline Bhaskaran, Krishnan Smeeth, Liam Richards, Marcus Schmidt, Sigrun A.J. Langan, Sinéad M. Warren-Gash, Charlotte J Alzheimers Dis Research Article BACKGROUND: In the UK, an estimated one third of people with dementia have not received a diagnosis. Good evidence suggests that dementia risk is increased among widowed individuals; however, it is not clear if they are being diagnosed in routine primary care. OBJECTIVE: This study aimed to investigate if bereavement influenced the probability of having received a dementia diagnosis. METHODS: A population-based cohort study using UK electronic health records, between 1997 and 2017, among 247,586 opposite-sex partners. Those experiencing partner bereavement were matched (age, sex, and date of bereavement) to a non-bereaved person living in a partnership. Multivariate cox regression was performed. RESULTS: Partner bereavement was associated with an increased risk of receiving a diagnosis of dementia in the first three months (hazard ratio (HR) 1.43, 95% CI 1.20–1.71) and first six months (HR 1.24, 95% CI 1.09–1.41), while there was a small reduced risk of getting a dementia diagnosis over all follow-up (HR 0.94, 95% CI 0.89–0.98). CONCLUSIONS: Partner bereavement appears to lead to a short-term increased risk of the surviving partner receiving a diagnosis of dementia, suggesting that bereavement unmasks existing undiagnosed dementia. Over the longer term, however, bereaved individuals are less likely to have a diagnosis of dementia in their health records than non-bereaved individuals. IOS Press 2019-11-12 /pmc/articles/PMC6918907/ /pubmed/31594227 http://dx.doi.org/10.3233/JAD-190571 Text en © 2019 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Article Forbes, Harriet J. Wong, Angel Y.S. Morton, Caroline Bhaskaran, Krishnan Smeeth, Liam Richards, Marcus Schmidt, Sigrun A.J. Langan, Sinéad M. Warren-Gash, Charlotte Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data |
title | Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data |
title_full | Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data |
title_fullStr | Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data |
title_full_unstemmed | Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data |
title_short | Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data |
title_sort | partner bereavement and detection of dementia: a uk-based cohort study using routine health data |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918907/ https://www.ncbi.nlm.nih.gov/pubmed/31594227 http://dx.doi.org/10.3233/JAD-190571 |
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