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A Bayesian Monte Carlo approach for predicting the spread of infectious diseases

In this paper, a simple yet interpretable, probabilistic model is proposed for the prediction of reported case counts of infectious diseases. A spatio-temporal kernel is derived from training data to capture the typical interaction effects of reported infections across time and space, which provides...

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Autores principales: Stojanović, Olivera, Leugering, Johannes, Pipa, Gordon, Ghozzi, Stéphane, Ullrich, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919583/
https://www.ncbi.nlm.nih.gov/pubmed/31851680
http://dx.doi.org/10.1371/journal.pone.0225838
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author Stojanović, Olivera
Leugering, Johannes
Pipa, Gordon
Ghozzi, Stéphane
Ullrich, Alexander
author_facet Stojanović, Olivera
Leugering, Johannes
Pipa, Gordon
Ghozzi, Stéphane
Ullrich, Alexander
author_sort Stojanović, Olivera
collection PubMed
description In this paper, a simple yet interpretable, probabilistic model is proposed for the prediction of reported case counts of infectious diseases. A spatio-temporal kernel is derived from training data to capture the typical interaction effects of reported infections across time and space, which provides insight into the dynamics of the spread of infectious diseases. Testing the model on a one-week-ahead prediction task for campylobacteriosis and rotavirus infections across Germany, as well as Lyme borreliosis across the federal state of Bavaria, shows that the proposed model performs on-par with the state-of-the-art hhh4 model. However, it provides a full posterior distribution over parameters in addition to model predictions, which aides in the assessment of the model. The employed Bayesian Monte Carlo regression framework is easily extensible and allows for incorporating prior domain knowledge, which makes it suitable for use on limited, yet complex datasets as often encountered in epidemiology.
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spelling pubmed-69195832019-12-27 A Bayesian Monte Carlo approach for predicting the spread of infectious diseases Stojanović, Olivera Leugering, Johannes Pipa, Gordon Ghozzi, Stéphane Ullrich, Alexander PLoS One Research Article In this paper, a simple yet interpretable, probabilistic model is proposed for the prediction of reported case counts of infectious diseases. A spatio-temporal kernel is derived from training data to capture the typical interaction effects of reported infections across time and space, which provides insight into the dynamics of the spread of infectious diseases. Testing the model on a one-week-ahead prediction task for campylobacteriosis and rotavirus infections across Germany, as well as Lyme borreliosis across the federal state of Bavaria, shows that the proposed model performs on-par with the state-of-the-art hhh4 model. However, it provides a full posterior distribution over parameters in addition to model predictions, which aides in the assessment of the model. The employed Bayesian Monte Carlo regression framework is easily extensible and allows for incorporating prior domain knowledge, which makes it suitable for use on limited, yet complex datasets as often encountered in epidemiology. Public Library of Science 2019-12-18 /pmc/articles/PMC6919583/ /pubmed/31851680 http://dx.doi.org/10.1371/journal.pone.0225838 Text en © 2019 Stojanović et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Stojanović, Olivera
Leugering, Johannes
Pipa, Gordon
Ghozzi, Stéphane
Ullrich, Alexander
A Bayesian Monte Carlo approach for predicting the spread of infectious diseases
title A Bayesian Monte Carlo approach for predicting the spread of infectious diseases
title_full A Bayesian Monte Carlo approach for predicting the spread of infectious diseases
title_fullStr A Bayesian Monte Carlo approach for predicting the spread of infectious diseases
title_full_unstemmed A Bayesian Monte Carlo approach for predicting the spread of infectious diseases
title_short A Bayesian Monte Carlo approach for predicting the spread of infectious diseases
title_sort bayesian monte carlo approach for predicting the spread of infectious diseases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919583/
https://www.ncbi.nlm.nih.gov/pubmed/31851680
http://dx.doi.org/10.1371/journal.pone.0225838
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