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TRPC3 determines osmosensitive [Ca(2+)](i) signaling in the collecting duct and contributes to urinary concentration
It is well-established that the kidney collecting duct (CD) plays a central role in regulation of systemic water homeostasis. Aquaporin 2 (AQP2)-dependent water reabsorption in the CD critically depends on the arginine vasopressin (AVP) antidiuretic input and the presence of a favorable osmotic grad...
Autores principales: | Tomilin, Viktor N., Mamenko, Mykola, Zaika, Oleg, Ren, Guohui, Marrelli, Sean P., Birnbaumer, Lutz, Pochynyuk, Oleh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919627/ https://www.ncbi.nlm.nih.gov/pubmed/31851715 http://dx.doi.org/10.1371/journal.pone.0226381 |
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