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The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored. Here, we established an integrated screening strategy to discover lncRNAs implicated in neurotransmitter and synaptic vesicle release. With...

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Detalles Bibliográficos
Autores principales: Keihani, S., Kluever, V., Mandad, S., Bansal, V., Rahman, R., Fritsch, E., Gomes, L. Caldi, Gärtner, A., Kügler, S., Urlaub, H., Wren, J. D., Bonn, S., Rizzoli, S. O., Fornasiero, E. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920028/
https://www.ncbi.nlm.nih.gov/pubmed/31897430
http://dx.doi.org/10.1126/sciadv.aay2670