Cargando…

Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study

PURPOSE: Probiotic supplementation demonstrates beneficial effects on serum lipid profiles. We hypothesized that probiotics could benefit patients presenting with alopecia, secondary to improved blood flow to the scalp. MATERIALS AND METHODS: Our study included men with stage II to V patterns of hai...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Dong-Wook, Lee, Hyo Serk, Shim, Myeong-Seung, Yum, Kyu Jin, Seo, Ju Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920077/
https://www.ncbi.nlm.nih.gov/pubmed/31385480
http://dx.doi.org/10.5534/wjmh.180119
_version_ 1783480870769786880
author Park, Dong-Wook
Lee, Hyo Serk
Shim, Myeong-Seung
Yum, Kyu Jin
Seo, Ju Tae
author_facet Park, Dong-Wook
Lee, Hyo Serk
Shim, Myeong-Seung
Yum, Kyu Jin
Seo, Ju Tae
author_sort Park, Dong-Wook
collection PubMed
description PURPOSE: Probiotic supplementation demonstrates beneficial effects on serum lipid profiles. We hypothesized that probiotics could benefit patients presenting with alopecia, secondary to improved blood flow to the scalp. MATERIALS AND METHODS: Our study included men with stage II to V patterns of hair loss based on the Hamilton–Norwood classification and women with stage I to III patterns of hair loss based on the Ludwig classification. All patients were administered 80 mL of Mogut® (a kimchi and cheonggukjang probiotic product) twice a day. Hair growth and numbers were measured using the Triple Scope System® (KC Technology, Korea) at baseline and after 1 and 4 months of administration of a kimchi and cheonggukjang probiotic product. RESULTS: At baseline, the mean hair count was 85.98±20.54 hairs/cm(2) and the mean thickness was 0.062±0.011 mm in all patients (n=46). Hair count and thickness had significantly increased at 1 month (90.28±16.13 hairs/cm(2) and 0.068±0.008 mm, respectively) and at 4 months (91.54±16.29 hairs/cm(2) and 0.066±0.009 mm, respectively). In this study, we found that a kimchi and cheonggukjang probiotic product could promote hair growth and reverse hair loss without associated adverse effects such as diarrhea. CONCLUSIONS: We suggest that the observed improvements in hair count and thickness resulted from initiation of the anagen phase in hair follicles in response to probiotics.
format Online
Article
Text
id pubmed-6920077
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Korean Society for Sexual Medicine and Andrology
record_format MEDLINE/PubMed
spelling pubmed-69200772020-01-01 Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study Park, Dong-Wook Lee, Hyo Serk Shim, Myeong-Seung Yum, Kyu Jin Seo, Ju Tae World J Mens Health Original Article PURPOSE: Probiotic supplementation demonstrates beneficial effects on serum lipid profiles. We hypothesized that probiotics could benefit patients presenting with alopecia, secondary to improved blood flow to the scalp. MATERIALS AND METHODS: Our study included men with stage II to V patterns of hair loss based on the Hamilton–Norwood classification and women with stage I to III patterns of hair loss based on the Ludwig classification. All patients were administered 80 mL of Mogut® (a kimchi and cheonggukjang probiotic product) twice a day. Hair growth and numbers were measured using the Triple Scope System® (KC Technology, Korea) at baseline and after 1 and 4 months of administration of a kimchi and cheonggukjang probiotic product. RESULTS: At baseline, the mean hair count was 85.98±20.54 hairs/cm(2) and the mean thickness was 0.062±0.011 mm in all patients (n=46). Hair count and thickness had significantly increased at 1 month (90.28±16.13 hairs/cm(2) and 0.068±0.008 mm, respectively) and at 4 months (91.54±16.29 hairs/cm(2) and 0.066±0.009 mm, respectively). In this study, we found that a kimchi and cheonggukjang probiotic product could promote hair growth and reverse hair loss without associated adverse effects such as diarrhea. CONCLUSIONS: We suggest that the observed improvements in hair count and thickness resulted from initiation of the anagen phase in hair follicles in response to probiotics. Korean Society for Sexual Medicine and Andrology 2020-01 2019-08-05 /pmc/articles/PMC6920077/ /pubmed/31385480 http://dx.doi.org/10.5534/wjmh.180119 Text en Copyright © 2020 Korean Society for Sexual Medicine and Andrology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Park, Dong-Wook
Lee, Hyo Serk
Shim, Myeong-Seung
Yum, Kyu Jin
Seo, Ju Tae
Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study
title Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study
title_full Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study
title_fullStr Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study
title_full_unstemmed Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study
title_short Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study
title_sort do kimchi and cheonggukjang probiotics as a functional food improve androgenetic alopecia? a clinical pilot study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920077/
https://www.ncbi.nlm.nih.gov/pubmed/31385480
http://dx.doi.org/10.5534/wjmh.180119
work_keys_str_mv AT parkdongwook dokimchiandcheonggukjangprobioticsasafunctionalfoodimproveandrogeneticalopeciaaclinicalpilotstudy
AT leehyoserk dokimchiandcheonggukjangprobioticsasafunctionalfoodimproveandrogeneticalopeciaaclinicalpilotstudy
AT shimmyeongseung dokimchiandcheonggukjangprobioticsasafunctionalfoodimproveandrogeneticalopeciaaclinicalpilotstudy
AT yumkyujin dokimchiandcheonggukjangprobioticsasafunctionalfoodimproveandrogeneticalopeciaaclinicalpilotstudy
AT seojutae dokimchiandcheonggukjangprobioticsasafunctionalfoodimproveandrogeneticalopeciaaclinicalpilotstudy