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The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks
Parasites have evolved various mechanisms to favor infection of their hosts and enhance the success of the infection. In this respect, time-of-day effects were found during the course of parasitic infections, which can be caused or controlled by circadian rhythms in the physiology of their vertebrat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920103/ https://www.ncbi.nlm.nih.gov/pubmed/31921702 http://dx.doi.org/10.3389/fcimb.2019.00425 |
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author | Carvalho Cabral, Priscilla Olivier, Martin Cermakian, Nicolas |
author_facet | Carvalho Cabral, Priscilla Olivier, Martin Cermakian, Nicolas |
author_sort | Carvalho Cabral, Priscilla |
collection | PubMed |
description | Parasites have evolved various mechanisms to favor infection of their hosts and enhance the success of the infection. In this respect, time-of-day effects were found during the course of parasitic infections, which can be caused or controlled by circadian rhythms in the physiology of their vertebrate hosts. These include circadian clock-controlled rhythms in metabolism and in immune responses. Conversely, parasites can also modulate their hosts' behavioral and cellular rhythms. Lastly, parasites themselves were in some cases shown to possess their own circadian clock mechanisms, which can influence their capacity to infect their hosts. A better knowledge of the circadian regulation of host-parasite interactions will help in designing new preventive and therapeutic strategies for parasitic diseases. |
format | Online Article Text |
id | pubmed-6920103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-69201032020-01-09 The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks Carvalho Cabral, Priscilla Olivier, Martin Cermakian, Nicolas Front Cell Infect Microbiol Cellular and Infection Microbiology Parasites have evolved various mechanisms to favor infection of their hosts and enhance the success of the infection. In this respect, time-of-day effects were found during the course of parasitic infections, which can be caused or controlled by circadian rhythms in the physiology of their vertebrate hosts. These include circadian clock-controlled rhythms in metabolism and in immune responses. Conversely, parasites can also modulate their hosts' behavioral and cellular rhythms. Lastly, parasites themselves were in some cases shown to possess their own circadian clock mechanisms, which can influence their capacity to infect their hosts. A better knowledge of the circadian regulation of host-parasite interactions will help in designing new preventive and therapeutic strategies for parasitic diseases. Frontiers Media S.A. 2019-12-12 /pmc/articles/PMC6920103/ /pubmed/31921702 http://dx.doi.org/10.3389/fcimb.2019.00425 Text en Copyright © 2019 Carvalho Cabral, Olivier and Cermakian. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cellular and Infection Microbiology Carvalho Cabral, Priscilla Olivier, Martin Cermakian, Nicolas The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks |
title | The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks |
title_full | The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks |
title_fullStr | The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks |
title_full_unstemmed | The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks |
title_short | The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks |
title_sort | complex interplay of parasites, their hosts, and circadian clocks |
topic | Cellular and Infection Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920103/ https://www.ncbi.nlm.nih.gov/pubmed/31921702 http://dx.doi.org/10.3389/fcimb.2019.00425 |
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