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Proton channel blockers inhibit Duox activity independent of Hv1 effects

The NADPH oxidase reaction produces protons. In the case of the NADPH oxidase, NOX2, activity depends on secretion of these protons and is inhibited by blockade of the voltage-gated proton channel (Hv1). Duox1 and Duox2 activities similarly produce intracellular protons but synthesize hydrogen perox...

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Detalles Bibliográficos
Autores principales:	Gattas, Monica Valencia, Jaffe, Adam, Barahona, Juliana, Conner, Gregory E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920136/ https://www.ncbi.nlm.nih.gov/pubmed/31678720 http://dx.doi.org/10.1016/j.redox.2019.101346

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