Angiotensin II Type I Receptor Antagonism Attenuates Nicotine-Induced Cardiac Remodeling, Dysfunction, and Aggravation of Myocardial Ischemia-Reperfusion Injury in Rats

Increased exposure to nicotine contributes to the development of cardiac dysfunction by promoting oxidative stress, fibrosis, and inflammation. These deleterious events altogether render cardiac myocytes more susceptible to acute cardiac insults such as ischemia-reperfusion (I/R) injury. This study...

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Detalles Bibliográficos
Autores principales: Ramalingam, Anand, Budin, Siti Balkis, Mohd. Fauzi, Norsyahida, Ritchie, Rebecca H., Zainalabidin, Satirah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920178/
https://www.ncbi.nlm.nih.gov/pubmed/31920673
http://dx.doi.org/10.3389/fphar.2019.01493

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