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Cerebral phaeohyphomycosis caused by Alternaria spp.: A case report

Phaeohyphomycosis is a group of infections caused by pigmented, black, dematiaceous fungi and is responsible for cutaneous, superficial and deep mycoses, disseminated infection and brain abscesses. The primary agents involved include Alternaria spp., Exophiala spp. and Cladophialophora spp. Invasive...

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Detalles Bibliográficos
Autores principales: Cardona, Santiago, Yusef, Soad, Silva, Edwin, Bustos M, Gisell, Torres M, Isabel, Leal A, Rafael, Ceballos-Garzon, Andres, Josa, Diego Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920265/
https://www.ncbi.nlm.nih.gov/pubmed/31879586
http://dx.doi.org/10.1016/j.mmcr.2019.12.001
Descripción
Sumario:Phaeohyphomycosis is a group of infections caused by pigmented, black, dematiaceous fungi and is responsible for cutaneous, superficial and deep mycoses, disseminated infection and brain abscesses. The primary agents involved include Alternaria spp., Exophiala spp. and Cladophialophora spp. Invasive systemic presentation is rare and in most cases is associated with immunosuppression; for this reason, reported cases of Alternaria spp. infection are scarce. This report describes the case of a 66-year-old man with a history of renal transplantation from a cadaveric donor 1 year ago, which was considered as the primary risk factor. The characteristics of the infection, procedures performed, microbiological findings and treatment provided are described.