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A novel, sensitive dual-indicator cell line for detection and quantification of inducible, replication-competent latent HIV-1 from reservoir cells

Understanding the mechanisms involved in HIV infection and latency, and development of a cure, rely on the availability of sensitive research tools such as indicator cells, which allow rigorous quantification of viral activity. Here we describe the construction and validation of a novel dual-indicat...

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Detalles Bibliográficos
Autores principales: Salasc, Fanny, Gludish, David W., Jarvis, Isobel, Boliar, Saikat, Wills, Mark R., Russell, David G., Lever, Andrew M. L., Mok, Hoi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920355/
https://www.ncbi.nlm.nih.gov/pubmed/31852924
http://dx.doi.org/10.1038/s41598-019-55596-8