CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance

The use of taxanes has for decades been crucial for treatment of several cancers. A major limitation of these therapies is inherent or acquired drug resistance. A key to improved outcome of taxane-based therapies is to develop tools to predict and monitor drug efficacy and resistance in the clinical...

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Detalles Bibliográficos
Autores principales: Langebäck, Anette, Bacanu, Smaranda, Laursen, Henriette, Mout, Lisanne, Seki, Takahiro, Erkens-Schulze, Sigrun, Ramos, Anderson Daniel, Berggren, Anna, Cao, Yihai, Hartman, Johan, van Weerden, Wytske, Bergh, Jonas, Nordlund, Pär, Lööf, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920357/
https://www.ncbi.nlm.nih.gov/pubmed/31852908
http://dx.doi.org/10.1038/s41598-019-55526-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920357/
https://www.ncbi.nlm.nih.gov/pubmed/31852908
http://dx.doi.org/10.1038/s41598-019-55526-8

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