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Focused ultrasound enhanced intranasal delivery of brain derived neurotrophic factor produces neurorestorative effects in a Parkinson’s disease mouse model
Focused ultrasound-enhanced intranasal (IN + FUS) delivery is a noninvasive approach that utilizes the olfactory pathway to administer pharmacological agents directly to the brain, allowing for a more homogenous distribution in targeted locations compared to IN delivery alone. However, whether such...
Autores principales: | Ji, Robin, Smith, Morgan, Niimi, Yusuke, Karakatsani, Maria E., Murillo, Maria F., Jackson-Lewis, Vernice, Przedborski, Serge, Konofagou, Elisa E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920380/ https://www.ncbi.nlm.nih.gov/pubmed/31852909 http://dx.doi.org/10.1038/s41598-019-55294-5 |
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