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A Unilateral Nasal Mass With Generalized Seizures: Potential Diagnostic Pitfalls in Giant Pituitary Adenoma
Giant pituitary adenomas are clinically nonfunctioning adenomas, and the clinical presentation is usually secondary to compression of the neighboring structures. Visual impairment and visual field defect are the most common preoperative symptoms, followed by headache. Generalized seizures may occur...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920587/ https://www.ncbi.nlm.nih.gov/pubmed/31897352 http://dx.doi.org/10.1177/2152656719896580 |
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author | Aini, Rahimah Sachlin, Ida Sadja’ah Chee, Lai Chuang Abdullah, Baharudin |
author_facet | Aini, Rahimah Sachlin, Ida Sadja’ah Chee, Lai Chuang Abdullah, Baharudin |
author_sort | Aini, Rahimah |
collection | PubMed |
description | Giant pituitary adenomas are clinically nonfunctioning adenomas, and the clinical presentation is usually secondary to compression of the neighboring structures. Visual impairment and visual field defect are the most common preoperative symptoms, followed by headache. Generalized seizures may occur in giant pituitary adenomas when there is involvement of frontal lobes or medial temporal lobes. We present a case of a unilateral nasal mass with generalized seizures in a 55-year-old woman without prior episode of seizure and any predisposing factors. Imaging showed a sinonasal tumor with intracranial extension and histopathological examination confirmed a corticotroph adenoma. On seeing a patient with a unilateral nasal mass extending down from the roof of nasal cavity, olfactory neuroblastoma, or meningo-encephalocoele readily comes to mind. To avoid misdiagnosis and delay in treatment, imaging and, if possible, a biopsy should be considered. Giant pituitary adenoma although not common should be thought of as one of the differential diagnosis. |
format | Online Article Text |
id | pubmed-6920587 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-69205872020-01-02 A Unilateral Nasal Mass With Generalized Seizures: Potential Diagnostic Pitfalls in Giant Pituitary Adenoma Aini, Rahimah Sachlin, Ida Sadja’ah Chee, Lai Chuang Abdullah, Baharudin Allergy Rhinol (Providence) Case Report Giant pituitary adenomas are clinically nonfunctioning adenomas, and the clinical presentation is usually secondary to compression of the neighboring structures. Visual impairment and visual field defect are the most common preoperative symptoms, followed by headache. Generalized seizures may occur in giant pituitary adenomas when there is involvement of frontal lobes or medial temporal lobes. We present a case of a unilateral nasal mass with generalized seizures in a 55-year-old woman without prior episode of seizure and any predisposing factors. Imaging showed a sinonasal tumor with intracranial extension and histopathological examination confirmed a corticotroph adenoma. On seeing a patient with a unilateral nasal mass extending down from the roof of nasal cavity, olfactory neuroblastoma, or meningo-encephalocoele readily comes to mind. To avoid misdiagnosis and delay in treatment, imaging and, if possible, a biopsy should be considered. Giant pituitary adenoma although not common should be thought of as one of the differential diagnosis. SAGE Publications 2019-12-17 /pmc/articles/PMC6920587/ /pubmed/31897352 http://dx.doi.org/10.1177/2152656719896580 Text en © The Author(s) 2019 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Aini, Rahimah Sachlin, Ida Sadja’ah Chee, Lai Chuang Abdullah, Baharudin A Unilateral Nasal Mass With Generalized Seizures: Potential Diagnostic Pitfalls in Giant Pituitary Adenoma |
title | A Unilateral Nasal Mass With Generalized Seizures: Potential
Diagnostic Pitfalls in Giant Pituitary Adenoma |
title_full | A Unilateral Nasal Mass With Generalized Seizures: Potential
Diagnostic Pitfalls in Giant Pituitary Adenoma |
title_fullStr | A Unilateral Nasal Mass With Generalized Seizures: Potential
Diagnostic Pitfalls in Giant Pituitary Adenoma |
title_full_unstemmed | A Unilateral Nasal Mass With Generalized Seizures: Potential
Diagnostic Pitfalls in Giant Pituitary Adenoma |
title_short | A Unilateral Nasal Mass With Generalized Seizures: Potential
Diagnostic Pitfalls in Giant Pituitary Adenoma |
title_sort | unilateral nasal mass with generalized seizures: potential
diagnostic pitfalls in giant pituitary adenoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920587/ https://www.ncbi.nlm.nih.gov/pubmed/31897352 http://dx.doi.org/10.1177/2152656719896580 |
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