Cargando…

Combinatorial conditioning of adipose derived‐mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration

BACKGROUND: Mesenchymal stem cells (MSCs) are becoming an increasingly attractive option for regenerative therapies due to their availability, self‐renewal capacity, multilineage potential, and anti‐inflammatory properties. Clinical trials are underway to test the efficacy of stem cell‐based therapi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Binch, Abbie. L. A., Richardson, Stephen M., Hoyland, Judith A., Barry, Frank P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920684/ https://www.ncbi.nlm.nih.gov/pubmed/31891121 http://dx.doi.org/10.1002/jsp2.1072

Ejemplares similares

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
por: Millward-Sadler, S Jane, et al.
Publicado: (2009)

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes
por: Minogue, Ben M, et al.
Publicado: (2010)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Importance of Matrix Cues on Intervertebral Disc Development, Degeneration, and Regeneration
por: Kibble, Matthew J., et al.
Publicado: (2022)

Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc
por: Tolofari, Sotonye K, et al.
Publicado: (2010)

Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration
por: LA Binch, Abbie, et al.
Publicado: (2014)

Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc
por: Purmessur, Devina, et al.
Publicado: (2008)

Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapies for intervertebral disc degeneration
por: Rodrigues-Pinto, R., et al.
Publicado: (2013)

Nerves are more abundant than blood vessels in the degenerate human intervertebral disc
por: Binch, Abbie L. A., et al.
Publicado: (2015)

The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2005)

Self-Assembling Peptide Hydrogels as Functional Tools to Tackle Intervertebral Disc Degeneration
por: Ligorio, Cosimo, et al.
Publicado: (2022)

High BMPR2 expression leads to enhanced SMAD1/5/8 signalling and GDF6 responsiveness in human adipose-derived stem cells: implications for stem cell therapies for intervertebral disc degeneration
por: Hodgkinson, Tom, et al.
Publicado: (2020)

Immunohistochemical analysis of protein expression in formalin fixed paraffin embedded human intervertebral disc tissues
por: Binch, Abbie, et al.
Publicado: (2020)

Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc
por: Binch, Abbie L. A., et al.
Publicado: (2015)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc
por: Richardson, Stephen M, et al.
Publicado: (2009)

Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells
por: Hodson, Nathan W., et al.
Publicado: (2018)

Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration
por: Heathfield, Sarah Kathleen, et al.
Publicado: (2008)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target
por: Gilbert, Hamish T. J., et al.
Publicado: (2016)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Mesenchymal stem cell therapies for intervertebral disc degeneration: Consideration of the degenerate niche
por: Vickers, Louise, et al.
Publicado: (2019)

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
por: Sano, Tomohiko, et al.
Publicado: (2019)

Mesenchymal Stem Cell for Prevention and Management of Intervertebral Disc Degeneration
por: Longo, Umile Giuseppe, et al.
Publicado: (2012)

Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells
por: Johnson, Zariel I., et al.
Publicado: (2015)

Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells
por: Le Maitre, Christine L, et al.
Publicado: (2009)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Bioactive lipids in intervertebral disc degeneration and its therapeutic implications
por: Das, Undurti N.
Publicado: (2019)

Role of Pyroptosis in Intervertebral Disc Degeneration and Its Therapeutic Implications
por: Luo, Jieya, et al.
Publicado: (2022)

Pyroptosis and Intervertebral Disc Degeneration: Mechanistic Insights and Therapeutic Implications
por: Ge, Yuying, et al.
Publicado: (2022)

Regulated cell death: Implications for intervertebral disc degeneration and therapy
por: Yang, Fan, et al.
Publicado: (2022)

The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration
por: Dudek, Michal, et al.
Publicado: (2017)

Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration
por: Jones, Philip, et al.
Publicado: (2008)

A Review: Methodologies to Promote the Differentiation of Mesenchymal Stem Cells for the Regeneration of Intervertebral Disc Cells Following Intervertebral Disc Degeneration
por: Ohnishi, Takashi, et al.
Publicado: (2023)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gnbqpnpeb3p1nuusgk8njb6uvm