Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report

Leiomyosarcoma of the stomach is an extremely rare malignancy for which treatment in advanced disease is hardly reported. Here, we report a case of a 48-year-old man with metastatic gastric Leiomyosarcoma who had previously received a combination of gemcitabine and docetaxel followed by pazopanib af...

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Autores principales: Rastogi, Sameer, Kalra, Kaushal, Manasa, Parisa, Rajawat, Monali, Mehta, Varshil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920747/
https://www.ncbi.nlm.nih.gov/pubmed/31915533
http://dx.doi.org/10.2144/fsoa-2019-0085
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author Rastogi, Sameer
Kalra, Kaushal
Manasa, Parisa
Rajawat, Monali
Mehta, Varshil
author_facet Rastogi, Sameer
Kalra, Kaushal
Manasa, Parisa
Rajawat, Monali
Mehta, Varshil
author_sort Rastogi, Sameer
collection PubMed
description Leiomyosarcoma of the stomach is an extremely rare malignancy for which treatment in advanced disease is hardly reported. Here, we report a case of a 48-year-old man with metastatic gastric Leiomyosarcoma who had previously received a combination of gemcitabine and docetaxel followed by pazopanib after detection of metastasis. The patient was started on trabectedin as per protocol and had disease control continuing for 17 cycles of trabectedin. His quality of life and absence of significant toxicities highlight the noncumulative nature of trabectedin and potential benefit in responding cases.
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spelling pubmed-69207472020-01-08 Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report Rastogi, Sameer Kalra, Kaushal Manasa, Parisa Rajawat, Monali Mehta, Varshil Future Sci OA Case Report Leiomyosarcoma of the stomach is an extremely rare malignancy for which treatment in advanced disease is hardly reported. Here, we report a case of a 48-year-old man with metastatic gastric Leiomyosarcoma who had previously received a combination of gemcitabine and docetaxel followed by pazopanib after detection of metastasis. The patient was started on trabectedin as per protocol and had disease control continuing for 17 cycles of trabectedin. His quality of life and absence of significant toxicities highlight the noncumulative nature of trabectedin and potential benefit in responding cases. Future Science Ltd 2019-12-09 /pmc/articles/PMC6920747/ /pubmed/31915533 http://dx.doi.org/10.2144/fsoa-2019-0085 Text en © 2019 Varshil Mehta This work is licensed under the http://creativecommons.org/licenses/by/4.0/
spellingShingle Case Report
Rastogi, Sameer
Kalra, Kaushal
Manasa, Parisa
Rajawat, Monali
Mehta, Varshil
Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
title Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
title_full Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
title_fullStr Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
title_full_unstemmed Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
title_short Long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
title_sort long lasting response of trabectedin in patient with gastric leiomyosarcoma with liver metastasis: an update to previous report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920747/
https://www.ncbi.nlm.nih.gov/pubmed/31915533
http://dx.doi.org/10.2144/fsoa-2019-0085
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