Pharmacokinetic Alteration of Paclitaxel by Ferulic Acid Derivative

P-glycoprotein (P-gp) is known to be involved in multidrug resistance (MDR) and modulation of pharmacokinetic (PK) profiles of substrate drugs. Here, we studied the effects of synthesized ferulic acid (FA) derivatives on P-gp function in vitro and examined PK alteration of paclitaxel (PTX), a well-k...

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Detalles Bibliográficos
Autores principales: Lee, Jaeok, Chae, Song Wha, Ma, LianJi, Lim, So Yeon, Alnajjar, Sarah, Park Choo, Hea-Young, Lee, Hwa Jeong, Rhie, Sandy Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920777/
https://www.ncbi.nlm.nih.gov/pubmed/31717555
http://dx.doi.org/10.3390/pharmaceutics11110593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920777/
https://www.ncbi.nlm.nih.gov/pubmed/31717555
http://dx.doi.org/10.3390/pharmaceutics11110593

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