Evaluation of Novel Chalcone-Thiosemicarbazones Derivatives as Potential Anti-Leishmania amazonensis Agents and Its HSA Binding Studies

A series of seven chalcone-thiosemicarbazones (5a–5g) were synthesized and evaluated as potential new drugs (anti-leishmanial effect). Although four of the chalcone-thiosemicarbazones are already known, none of them or any compound in this class has been previously investigated for their effects on...

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Detalles Bibliográficos
Autores principales: Mendes, Edinéia Pastro, Goulart, Carla Marins, Chaves, Otávio Augusto, Faiões, Viviane dos S., Canto-Carvalho, Marilene M., Machado, Gerzia C., Torres-Santos, Eduardo Caio, Echevarria, Aurea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920794/
https://www.ncbi.nlm.nih.gov/pubmed/31652866
http://dx.doi.org/10.3390/biom9110643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920794/
https://www.ncbi.nlm.nih.gov/pubmed/31652866
http://dx.doi.org/10.3390/biom9110643

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