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Evaluation of Novel Chalcone-Thiosemicarbazones Derivatives as Potential Anti-Leishmania amazonensis Agents and Its HSA Binding Studies
A series of seven chalcone-thiosemicarbazones (5a–5g) were synthesized and evaluated as potential new drugs (anti-leishmanial effect). Although four of the chalcone-thiosemicarbazones are already known, none of them or any compound in this class has been previously investigated for their effects on...
Autores principales: | Mendes, Edinéia Pastro, Goulart, Carla Marins, Chaves, Otávio Augusto, Faiões, Viviane dos S., Canto-Carvalho, Marilene M., Machado, Gerzia C., Torres-Santos, Eduardo Caio, Echevarria, Aurea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920794/ https://www.ncbi.nlm.nih.gov/pubmed/31652866 http://dx.doi.org/10.3390/biom9110643 |
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