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Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?

Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the diagnosis and management of respiratory viral inf...

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Autores principales: Popescu, Cristian-Marian, Ursache, Aurora Livia, Feketea, Gavriela, Bocsan, Corina, Jimbu, Laura, Mesaros, Oana, Edwards, Michael, Wang, Hongwei, Berceanu, Iulia, Neaga, Alexandra, Zdrenghea, Mihnea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920795/
https://www.ncbi.nlm.nih.gov/pubmed/31684063
http://dx.doi.org/10.3390/microorganisms7110521
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author Popescu, Cristian-Marian
Ursache, Aurora Livia
Feketea, Gavriela
Bocsan, Corina
Jimbu, Laura
Mesaros, Oana
Edwards, Michael
Wang, Hongwei
Berceanu, Iulia
Neaga, Alexandra
Zdrenghea, Mihnea
author_facet Popescu, Cristian-Marian
Ursache, Aurora Livia
Feketea, Gavriela
Bocsan, Corina
Jimbu, Laura
Mesaros, Oana
Edwards, Michael
Wang, Hongwei
Berceanu, Iulia
Neaga, Alexandra
Zdrenghea, Mihnea
author_sort Popescu, Cristian-Marian
collection PubMed
description Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the diagnosis and management of respiratory viral infections in this setting, there is no uniform inclusion of respiratory viral infection management in the clinical hematology routine. Nevertheless, timely diagnosis and systematic management of CRV infections in intensively treated hematology patients has a demonstrated potential to significantly improve outcome. We have briefly summarized the recently published data on CRV infection epidemiology, as well as guidelines on the diagnosis and management of CRV infections in patients intensively treated for hematological malignancies. We have also assessed available treatment options, as well as mentioned novel agents currently in development.
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spelling pubmed-69207952019-12-24 Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients? Popescu, Cristian-Marian Ursache, Aurora Livia Feketea, Gavriela Bocsan, Corina Jimbu, Laura Mesaros, Oana Edwards, Michael Wang, Hongwei Berceanu, Iulia Neaga, Alexandra Zdrenghea, Mihnea Microorganisms Review Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the diagnosis and management of respiratory viral infections in this setting, there is no uniform inclusion of respiratory viral infection management in the clinical hematology routine. Nevertheless, timely diagnosis and systematic management of CRV infections in intensively treated hematology patients has a demonstrated potential to significantly improve outcome. We have briefly summarized the recently published data on CRV infection epidemiology, as well as guidelines on the diagnosis and management of CRV infections in patients intensively treated for hematological malignancies. We have also assessed available treatment options, as well as mentioned novel agents currently in development. MDPI 2019-11-02 /pmc/articles/PMC6920795/ /pubmed/31684063 http://dx.doi.org/10.3390/microorganisms7110521 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Popescu, Cristian-Marian
Ursache, Aurora Livia
Feketea, Gavriela
Bocsan, Corina
Jimbu, Laura
Mesaros, Oana
Edwards, Michael
Wang, Hongwei
Berceanu, Iulia
Neaga, Alexandra
Zdrenghea, Mihnea
Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
title Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
title_full Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
title_fullStr Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
title_full_unstemmed Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
title_short Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
title_sort are community acquired respiratory viral infections an underestimated burden in hematology patients?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920795/
https://www.ncbi.nlm.nih.gov/pubmed/31684063
http://dx.doi.org/10.3390/microorganisms7110521
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