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Design of N-Terminal Derivatives from a Novel Dermaseptin Exhibiting Broad-Spectrum Antimicrobial Activity against Isolates from Cystic Fibrosis Patients
Dermaseptins are an antimicrobial peptide family widely identified from the skin secretions of phyllomeudusinae frogs. Here, we identify Dermaseptin-PC (DM-PC), from the skin secretion of Phyllomedusa coelestis, and further investigate the properties of this peptide, and a number of rationally desig...
Autores principales: | Ying, Yuan, Wang, Hui, Xi, Xinping, Ma, Chengbang, Liu, Yue, Zhou, Mei, Du, Qiang, Burrows, James F., Wei, Minjie, Chen, Tianbao, Wang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920804/ https://www.ncbi.nlm.nih.gov/pubmed/31653005 http://dx.doi.org/10.3390/biom9110646 |
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