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The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli

Finasteride (FIN) is the prototypical inhibitor of steroid 5α-reductase (5αR), the enzyme that catalyzes the rate-limiting step of the conversion of progesterone and testosterone into their main neuroactive metabolites. FIN is clinically approved for the treatment of benign prostatic hyperplasia and...

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Detalles Bibliográficos
Autores principales: Godar, Sean C., Cadeddu, Roberto, Floris, Gabriele, Mosher, Laura J., Mi, Zhen, Jarmolowicz, David P., Scheggi, Simona, Walf, Alicia A., Koonce, Carolyn J., Frye, Cheryl A., Muma, Nancy A., Bortolato, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920809/
https://www.ncbi.nlm.nih.gov/pubmed/31752360
http://dx.doi.org/10.3390/biom9110749