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The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride (FIN) is the prototypical inhibitor of steroid 5α-reductase (5αR), the enzyme that catalyzes the rate-limiting step of the conversion of progesterone and testosterone into their main neuroactive metabolites. FIN is clinically approved for the treatment of benign prostatic hyperplasia and...
Autores principales: | Godar, Sean C., Cadeddu, Roberto, Floris, Gabriele, Mosher, Laura J., Mi, Zhen, Jarmolowicz, David P., Scheggi, Simona, Walf, Alicia A., Koonce, Carolyn J., Frye, Cheryl A., Muma, Nancy A., Bortolato, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920809/ https://www.ncbi.nlm.nih.gov/pubmed/31752360 http://dx.doi.org/10.3390/biom9110749 |
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