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IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening

Since most preclinical drug permeability assays across the blood-brain barrier (BBB) are still evaluated in rodents, we compared an in vitro mouse primary endothelial cell model to the mouse b.End3 and the acellular parallel artificial membrane permeability assay (PAMPA) models for drug screening pu...

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Detalles Bibliográficos
Autores principales:	Puscas, Ina, Bernard-Patrzynski, Florian, Jutras, Martin, Lécuyer, Marc-André, Bourbonnière, Lyne, Prat, Alexandre, Leclair, Grégoire, Roullin, V. Gaëlle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920823/ https://www.ncbi.nlm.nih.gov/pubmed/31717321 http://dx.doi.org/10.3390/pharmaceutics11110587

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