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Characterization of the Ohmyungsamycin Biosynthetic Pathway and Generation of Derivatives with Improved Antituberculosis Activity

The cyclic depsipeptides ohmyungsamycin (OMS) A (1) and B (2), isolated from the marine-derived Streptomyces sp. SNJ042, contain two non-proteinogenic amino acid residues, β-hydroxy-l-phenylalanine (β-hydroxy-l-Phe) and 4-methoxy-l-tryptophan (4-methoxy-l-Trp). Draft genome sequencing of Streptomyce...

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Detalles Bibliográficos
Autores principales:	Kim, Eunji, Shin, Yern-Hyerk, Kim, Tae Ho, Byun, Woong Sub, Cui, Jinsheng, Du, Young Eun, Lim, Hyung-Ju, Song, Myoung Chong, Kwon, An Sung, Kang, Sang Hyeon, Shin, Jongheon, Lee, Sang Kook, Jang, Jichan, Oh, Dong-Chan, Yoon, Yeo Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920865/ https://www.ncbi.nlm.nih.gov/pubmed/31671649 http://dx.doi.org/10.3390/biom9110672

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