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Development of Folate-Functionalized PEGylated Zein Nanoparticles for Ligand-Directed Delivery of Paclitaxel
In this study, we investigated the active targeted delivery of a hydrophobic drug, paclitaxel (PTX), via receptor-mediated endocytosis by folate receptors expressed on cancer cells using a protein-based nanoparticle system. PTX was loaded on zein nanoparticles and conjugated with folate (PTX/Zein-FA...
Autores principales: | Soe, Zar Chi, Ou, Wenquan, Gautam, Milan, Poudel, Kishwor, Kim, Bo Kyun, Pham, Le Minh, Phung, Cao Dai, Jeong, Jee-Heon, Jin, Sung Giu, Choi, Han-Gon, Ku, Sae Kwang, Yong, Chul Soon, Kim, Jong Oh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920870/ https://www.ncbi.nlm.nih.gov/pubmed/31671569 http://dx.doi.org/10.3390/pharmaceutics11110562 |
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