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Antibodies from the Sera of Multiple Sclerosis Patients Efficiently Hydrolyze Five Histones
It is known that intranuclear histones can be pernicious after entering to the extracellular space. In addition, the immunization of animals with exogenous histones leads to systemic inflammatory and toxic reactions. Abzymes—autoantibodies with enzymatic activities—are the distinctive feature of aut...
Autores principales: | Baranova, Svetlana V., Mikheeva, Elena V., Buneva, Valentina N., Nevinsky, Georgy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920934/ https://www.ncbi.nlm.nih.gov/pubmed/31731780 http://dx.doi.org/10.3390/biom9110741 |
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