Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions

The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated this drug for the topical treatment of CL. As efficacy depends on potency and skin penetration, we first det...

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Detalles Bibliográficos
Autores principales: Moreno, Esther, Calvo, Alba, Schwartz, Juana, Navarro-Blasco, Iñigo, González-Peñas, Elena, Sanmartín, Carmen, Irache, Juan Manuel, Espuelas, Socorro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920985/
https://www.ncbi.nlm.nih.gov/pubmed/31766282
http://dx.doi.org/10.3390/pharmaceutics11110607

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