Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship

Multidrug resistance (MDR) is often caused by the overexpression of efflux pumps, such as ABC transporters, in particular, P-glycoprotein (P-gp). Here, we investigate the di- and tri- block amphiphilic polymer systems based on polypropylene glycol (PPO) and copolymers of (N-(2-hydroxypropyl)methacry...

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Detalles Bibliográficos
Autores principales: Braunová, Alena, Kaňa, Martin, Kudláčová, Júlia, Kostka, Libor, Bouček, Jan, Betka, Jan, Šírová, Milada, Etrych, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920990/
https://www.ncbi.nlm.nih.gov/pubmed/31694350
http://dx.doi.org/10.3390/pharmaceutics11110579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920990/
https://www.ncbi.nlm.nih.gov/pubmed/31694350
http://dx.doi.org/10.3390/pharmaceutics11110579

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