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Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship
Multidrug resistance (MDR) is often caused by the overexpression of efflux pumps, such as ABC transporters, in particular, P-glycoprotein (P-gp). Here, we investigate the di- and tri- block amphiphilic polymer systems based on polypropylene glycol (PPO) and copolymers of (N-(2-hydroxypropyl)methacry...
Autores principales: | Braunová, Alena, Kaňa, Martin, Kudláčová, Júlia, Kostka, Libor, Bouček, Jan, Betka, Jan, Šírová, Milada, Etrych, Tomáš |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920990/ https://www.ncbi.nlm.nih.gov/pubmed/31694350 http://dx.doi.org/10.3390/pharmaceutics11110579 |
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