Structural Characterization of Full-Length Human Dehydrodolichyl Diphosphate Synthase Using an Integrative Computational and Experimental Approach

Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human cis-prenyltransferase complex, synthesizing the glycosyl carrier precursor for N-linked protein glycosylation. Consistent with the important role of N-glycosylation in protein biogenesis, DHDDS mutations r...

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Detalles Bibliográficos
Autores principales: Lisnyansky Bar-El, Michal, Lee, Su Youn, Ki, Ah Young, Kapelushnik, Noa, Loewenstein, Anat, Chung, Ka Young, Schneidman-Duhovny, Dina, Giladi, Moshe, Newman, Hadas, Haitin, Yoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921004/
https://www.ncbi.nlm.nih.gov/pubmed/31661879
http://dx.doi.org/10.3390/biom9110660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921004/
https://www.ncbi.nlm.nih.gov/pubmed/31661879
http://dx.doi.org/10.3390/biom9110660

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