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A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment

Transforming growth factor (TGF)-β is a secreted multifunctional cytokine that signals via plasma membrane TGF-β type I and type II receptors and intercellular SMAD transcriptional effectors. Aberrant inter- and intracellular TGF-β signaling can contribute to cancer progression. In normal cells and...

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Detalles Bibliográficos
Autores principales:	Huynh, Linh Khanh, Hipolito, Christopher John, ten Dijke, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921009/ https://www.ncbi.nlm.nih.gov/pubmed/31744193 http://dx.doi.org/10.3390/biom9110743

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