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The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
Allelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial frequencies, th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921034/ https://www.ncbi.nlm.nih.gov/pubmed/31739595 http://dx.doi.org/10.3390/microorganisms7110564 |
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author | Ghazaryan, Lusine Giladi, Itamar Gillor, Osnat |
author_facet | Ghazaryan, Lusine Giladi, Itamar Gillor, Osnat |
author_sort | Ghazaryan, Lusine |
collection | PubMed |
description | Allelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial frequencies, the structure of their habitat, their community density and their nutrient availability. These interactions were extensively studied in bacteriocins produced by Escherichia coli, the colicins. In spatially structured environments where interactions are local, colicin production has been shown to be advantageous to the producer population, allowing them to compete even when initially rare. Yet, in a well-mixed, unstructured environment where interactions are global, rare producer populations cannot invade a common sensitive population. Here we are showing, through an experimental model, that colicin-producers can outcompete sensitive and producer populations when the colicin production rates are enhanced. In fact, colicin production rates were proportional to the producer competitive fitness and their overall success in out-competing opponents when invading at very low initial frequencies. This ability of rare populations to invade established communities maintains diversity and allows the dispersal of beneficial traits. |
format | Online Article Text |
id | pubmed-6921034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69210342019-12-24 The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations Ghazaryan, Lusine Giladi, Itamar Gillor, Osnat Microorganisms Article Allelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial frequencies, the structure of their habitat, their community density and their nutrient availability. These interactions were extensively studied in bacteriocins produced by Escherichia coli, the colicins. In spatially structured environments where interactions are local, colicin production has been shown to be advantageous to the producer population, allowing them to compete even when initially rare. Yet, in a well-mixed, unstructured environment where interactions are global, rare producer populations cannot invade a common sensitive population. Here we are showing, through an experimental model, that colicin-producers can outcompete sensitive and producer populations when the colicin production rates are enhanced. In fact, colicin production rates were proportional to the producer competitive fitness and their overall success in out-competing opponents when invading at very low initial frequencies. This ability of rare populations to invade established communities maintains diversity and allows the dispersal of beneficial traits. MDPI 2019-11-14 /pmc/articles/PMC6921034/ /pubmed/31739595 http://dx.doi.org/10.3390/microorganisms7110564 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ghazaryan, Lusine Giladi, Itamar Gillor, Osnat The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations |
title | The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations |
title_full | The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations |
title_fullStr | The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations |
title_full_unstemmed | The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations |
title_short | The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations |
title_sort | effects of colicin production rates on allelopathic interactions in escherichia coli populations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921034/ https://www.ncbi.nlm.nih.gov/pubmed/31739595 http://dx.doi.org/10.3390/microorganisms7110564 |
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