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The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations

Allelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial frequencies, th...

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Detalles Bibliográficos
Autores principales: Ghazaryan, Lusine, Giladi, Itamar, Gillor, Osnat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921034/
https://www.ncbi.nlm.nih.gov/pubmed/31739595
http://dx.doi.org/10.3390/microorganisms7110564
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author Ghazaryan, Lusine
Giladi, Itamar
Gillor, Osnat
author_facet Ghazaryan, Lusine
Giladi, Itamar
Gillor, Osnat
author_sort Ghazaryan, Lusine
collection PubMed
description Allelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial frequencies, the structure of their habitat, their community density and their nutrient availability. These interactions were extensively studied in bacteriocins produced by Escherichia coli, the colicins. In spatially structured environments where interactions are local, colicin production has been shown to be advantageous to the producer population, allowing them to compete even when initially rare. Yet, in a well-mixed, unstructured environment where interactions are global, rare producer populations cannot invade a common sensitive population. Here we are showing, through an experimental model, that colicin-producers can outcompete sensitive and producer populations when the colicin production rates are enhanced. In fact, colicin production rates were proportional to the producer competitive fitness and their overall success in out-competing opponents when invading at very low initial frequencies. This ability of rare populations to invade established communities maintains diversity and allows the dispersal of beneficial traits.
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spelling pubmed-69210342019-12-24 The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations Ghazaryan, Lusine Giladi, Itamar Gillor, Osnat Microorganisms Article Allelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial frequencies, the structure of their habitat, their community density and their nutrient availability. These interactions were extensively studied in bacteriocins produced by Escherichia coli, the colicins. In spatially structured environments where interactions are local, colicin production has been shown to be advantageous to the producer population, allowing them to compete even when initially rare. Yet, in a well-mixed, unstructured environment where interactions are global, rare producer populations cannot invade a common sensitive population. Here we are showing, through an experimental model, that colicin-producers can outcompete sensitive and producer populations when the colicin production rates are enhanced. In fact, colicin production rates were proportional to the producer competitive fitness and their overall success in out-competing opponents when invading at very low initial frequencies. This ability of rare populations to invade established communities maintains diversity and allows the dispersal of beneficial traits. MDPI 2019-11-14 /pmc/articles/PMC6921034/ /pubmed/31739595 http://dx.doi.org/10.3390/microorganisms7110564 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ghazaryan, Lusine
Giladi, Itamar
Gillor, Osnat
The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
title The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
title_full The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
title_fullStr The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
title_full_unstemmed The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
title_short The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli Populations
title_sort effects of colicin production rates on allelopathic interactions in escherichia coli populations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921034/
https://www.ncbi.nlm.nih.gov/pubmed/31739595
http://dx.doi.org/10.3390/microorganisms7110564
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