Cargando…

Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges

Human Mesenchymal Stem Cells (hMSCs) play an important role as new therapeutic alternatives in advanced therapies and regenerative medicine thanks to their regenerative and immunomodulatory properties, and ability to migrate to the exact area of injury. These properties have made hMSCs one of the mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guadix, Juan Antonio, López-Beas, Javier, Clares, Beatriz, Soriano-Ruiz, José Luis, Zugaza, José Luis, Gálvez-Martín, Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921040/ https://www.ncbi.nlm.nih.gov/pubmed/31652984 http://dx.doi.org/10.3390/pharmaceutics11110552

Ejemplares similares

Expansion and Harvesting of hMSC-TERT
por: Weber, Christian, et al.
Publicado: (2007)

BMP2 induces hMSC osteogenesis and matrix remodeling
por: Cai, Hantao, et al.
Publicado: (2021)

Therapeutic Effects of hMAPC and hMSC Transplantation after Stroke in Mice
por: Mora-Lee, Silvia, et al.
Publicado: (2012)

Implementation of soft microfingers for a hMSC aggregate manipulation system
por: Konishi, Satoshi, et al.
Publicado: (2016)

Mesenchymal Stem Cells as Therapeutics Agents: Quality and Environmental Regulatory Aspects
por: Galvez-Martin, Patricia, et al.
Publicado: (2016)

Comparison of the effects of 45S5 and 1393 bioactive glass microparticles on hMSC behavior
por: Qazi, Taimoor H., et al.
Publicado: (2017)

Regulation of endothelial cell arrangements within hMSC – HUVEC co-cultured aggregates
por: Deegan, Anthony J., et al.
Publicado: (2019)

hMSC exosomes as a novel treatment for female sensitive skin: An in vivo study
por: Ye, Congxiu, et al.
Publicado: (2022)

Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide
por: Cimino, Maura, et al.
Publicado: (2023)

Theoretical and Practical Issues That Are Relevant When Scaling Up hMSC Microcarrier Production Processes
por: Jossen, Valentin, et al.
Publicado: (2016)

An in vitro model system based on calcium- and phosphate ion-induced hMSC spheroid mineralization
por: Vermeulen, Steven, et al.
Publicado: (2023)

Glucosamine increases the expression of YKL-40 and osteogenic marker genes in hMSC during osteogenic differentiation
por: Lieder, Ramona, et al.
Publicado: (2012)

Metabolism in Human Mesenchymal Stromal Cells: A Missing Link Between hMSC Biomanufacturing and Therapy?
por: Yuan, Xuegang, et al.
Publicado: (2019)

Effect of Topography and Physical Stimulus on hMSC Phenotype Using a 3D In Vitro Model
por: Kumar, Deepak, et al.
Publicado: (2019)

Influence of osteogenic stimulation and VEGF treatment on in vivo bone formation in hMSC-seeded cancellous bone scaffolds
por: Lenze, Ulrich, et al.
Publicado: (2014)

Metabolic Glycoengineering in hMSC-TERT as a Model for Skeletal Precursors by Using Modified Azide/Alkyne Monosaccharides
por: Altmann, Stephan, et al.
Publicado: (2021)

Cultivation and Differentiation of Encapsulated hMSC-TERT in a Disposable Small-Scale Syringe-Like Fixed Bed Reactor
por: Weber, Christian, et al.
Publicado: (2007)

Human platelet lysate to substitute fetal bovine serum in hMSC expansion for translational applications: a systematic review
por: Guiotto, M., et al.
Publicado: (2020)

Toward a serum-free, xeno-free culture system for optimal growth and expansion of hMSC suited to therapeutic applications
por: Genser-Nir, Mira, et al.
Publicado: (2013)

Amnion and chorion matrix maintain hMSC osteogenic response and enhance immunomodulatory and angiogenic potential in a mineralized collagen scaffold
por: Kolliopoulos, Vasiliki, et al.
Publicado: (2022)

Mesoporous calcium–silicon xerogels with mesopore size and pore volume influence hMSC behaviors by load and sustained release of rhBMP-2
por: Song, Wenhua, et al.
Publicado: (2015)

Hydrogel-Embedded Poly(Lactic-co-Glycolic Acid) Microspheres for the Delivery of hMSC-Derived Exosomes to Promote Bioactive Annulus Fibrosus Repair
por: DiStefano, Tyler J., et al.
Publicado: (2022)

Human Mesenchymal Stem Cell (hMSC) Donor Potency Selection for the “First in Cystic Fibrosis” Phase I Clinical Trial (CEASE-CF)
por: Bonfield, Tracey L., et al.
Publicado: (2023)

Neuroprotective Potential and Paracrine Activity of Stromal Vs. Culture-Expanded hMSC Derived from Wharton Jelly under Co-Cultured with Hippocampal Organotypic Slices
por: Dabrowska, Sylwia, et al.
Publicado: (2017)

Joint species distribution modelling with the r‐package Hmsc
por: Tikhonov, Gleb, et al.
Publicado: (2020)

Sodium Hyaluronate Supplemented Culture Media as a New hMSC Chondrogenic Differentiation Media-Model for in vitro/ex vivo Screening of Potential Cartilage Repair Therapies
por: Monaco, Graziana, et al.
Publicado: (2020)

(99m)Tc-HDP Labeling—A Non-Destructive Method for Real-Time Surveillance of the Osteogenic Differentiation Potential of hMSC during Ongoing Cell Cultures
por: Hofmann, Jakob, et al.
Publicado: (2022)

The Restoring Effect of Human Umbilical Cord-Derived Mesenchymal Cell-Conditioned Medium (hMSC-CM) against Carbon Tetrachloride-Induced Pulmonary Fibrosis in Male Wistar Rats
por: Khajvand-Abedini, Maryam, et al.
Publicado: (2022)

12th Hungarian Conference on Materials Science (HMSC12)
por: Collective
Publicado: (2019)

Improved MSC Minimal Criteria to Maximize Patient Safety: A Call to Embrace Tissue Factor and Hemocompatibility Assessment of MSC Products
por: Moll, Guido, et al.
Publicado: (2022)

Rapidly Self-Renewing Human Multipotent Marrow Stromal Cells (hMSC) Express Sialyl Lewis X and Actively Adhere to Arterial Endothelium in a Chick Embryo Model System
por: McFerrin, Harris E., et al.
Publicado: (2014)

CCL1 blockade alleviates human mesenchymal stem cell (hMSC)-induced pulmonary fibrosis in a murine sclerodermatous graft-versus-host disease (Scl-GVHD) model
por: Lim, Ji-Young, et al.
Publicado: (2020)

Pharmacophore-based screening of differentially-expressed PGF, DDIT4, COMP and CHI3L1 from hMSC cell lines reveals five novel therapeutic compounds for primary osteoporosis
por: Lai, Catherine Jessica
Publicado: (2016)

Long noncoding RNA UCA1 from hypoxia-conditioned hMSC-derived exosomes: a novel molecular target for cardioprotection through miR-873-5p/XIAP axis
por: Sun, Ling, et al.
Publicado: (2020)

HmsC Controls Yersinia pestis Biofilm Formation in Response to Redox Environment
por: Ren, Gai-Xian, et al.
Publicado: (2017)

McArdle Disease: New Insights into Its Underlying Molecular Mechanisms
por: Llavero, Francisco, et al.
Publicado: (2019)

Mesenchymal stromal cells (MSC) from JAK2(+) myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesis
por: Ramos, Teresa L., et al.
Publicado: (2017)

Corrigendum: HmsC Controls Yersinia pestis Biofilm Formation in Response to Redox Environment
por: Ren, Gai-Xian, et al.
Publicado: (2018)

Small GTPases of the Ras and Rho Families Switch on/off Signaling Pathways in Neurodegenerative Diseases
por: Arrazola Sastre, Alazne, et al.
Publicado: (2020)

Down-Regulation of miR-301a-3p Reduces Burn-Induced Vascular Endothelial Apoptosis by potentiating hMSC-Secreted IGF-1 and PI3K/Akt/FOXO3a Pathway
por: Liu, Lingying, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5dv66f5ntvr9tpgucojnne1gi2